Dibutyl phthalate promotes juvenile Sertoli cell proliferation by decreasing the levels of the E3 ubiquitin ligase Pellino 2

• Main Authors: Tan Ma (Author), Jiwei Hou (Author), Yuan Zhou (Author), Yusheng Chen (Author), Jiayin Qiu (Author), Jiang Wu (Author), Jie Ding (Author), Xiaodong Han (Author), Dongmei Li (Author)
• Format: Book
• Published: BMC, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background A previous study showed that dibutyl phthalate (DBP) exposure disrupted the growth of testicular Sertoli cells (SCs). In the present study, we aimed to investigate the potential mechanism by which DBP promotes juvenile SC proliferation in vivo and in vitro. Methods Timed pregnant...