PVA-Microbubbles as a Radioembolization Platform: Formulation and the In Vitro Proof of Concept

• Main Authors: Valerio Da Ros (Author), Letizia Oddo (Author), Yosra Toumia (Author), Eugenia Guida (Author), Silvia Minosse (Author), Lidia Strigari (Author), Silvia Strolin (Author), Giulia Paolani (Author), Francesca Di Giuliano (Author), Roberto Floris (Author), Francesco Garaci (Author), Susanna Dolci (Author), Gaio Paradossi (Author), Fabio Domenici (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This proof-of-concept study lays the foundations for the development of a delivery strategy for radioactive lanthanides, such as Yttrium-90, against recurrent glioblastoma. Our appealing hypothesis is that by taking advantage of the combination of biocompatible polyvinyl alcohol (PVA) microbubbles (...