Metabolism and disposition of opicapone in the rat and metabolic enzymes phenotyping
Abstract Opicapone (2,5‐dichloro‐3‐(5‐(3,4‐dihydroxy‐5‐nitrophenyl)‐1,2,4‐oxadiazol‐3‐yl)‐4,6‐dimethylpyridine 1‐oxide) is a selective catechol‐O‐methyltransferase inhibitor that has been granted marketing authorization in Europe, Japan, and United States. The present work describes the metabolism a...
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Main Authors: | Ana I. Loureiro (Author), Carlos Fernandes‐Lopes (Author), Maria João Bonifácio (Author), Filipa Sousa (Author), László E. Kiss (Author), Patricio Soares‐da‐Silva (Author) |
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Format: | Book |
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Wiley,
2022-02-01T00:00:00Z.
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