Increased peripheral nerve excitability and local NaV1.8 mRNA up-regulation in painful neuropathy

• Main Authors: Matsuka Yoshizo (Author), Lin Audrey (Author), Thakor Devang (Author), Meyer Edward M (Author), Ruangsri Supanigar (Author), Nishimura Ichiro (Author), Spigelman Igor (Author)
• Format: Book
• Published: SAGE Publishing, 2009-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Neuropathic pain caused by peripheral nerve injury is a chronic disorder that represents a significant clinical challenge because the pathological mechanisms have not been fully elucidated. Several studies have suggested the involvem...