Assessment of drug-drug interaction potential with EDP‐305, a farnesoid X receptor agonist, in healthy subjects

Abstract EDP‐305 is a farnesoid X receptor (FXR) agonist that selectively activates FXR and is a potential treatment for patients with nonalcoholic steatohepatitis (NASH) with liver fibrosis. Results from preclinical studies indicate that CYP3A4 is the primary enzyme involved in EDP‐305 metabolism a...

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Auteurs principaux: Alaa Ahmad (Auteur), Nathalie Adda (Auteur)
Format: Livre
Publié: Wiley, 2022-09-01T00:00:00Z.
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