Prostaglandin E2 Affects Differently the Release of Inflammatory Mediators from Resident Macrophages by LPS and Muramyl Tripeptides

• Main Authors: Peter Dieter (Author), Ute Hempel (Author), Sabine Kamionka (Author), Angelika Kolada (Author), Birgit Malessa (Author), Edith Fitzke (Author), Thuy-An (Author)
• Format: Book
• Published: Hindawi Limited, 1999-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

LPS and MTP-PE (liposome-encapsulated N-acetylmuramyl-L-alanyl-D-isoglutaminyl-L-alanine-2-:[1',2'-dipalmitoyl-sni-glycero-3-(hydroxy-phosphoryl-oxyl)] etylamide) induce in liver macrophages a synthesis and release of TNF-α, nitric oxide and prostanoids. Both agents induce an expression of...