Long-Term Exposure of RN46A Cells Expressing Serotonin Transporter (SERT) to a cAMP Analog Up-regulates SERT Activity and Is Accompanied by Neural Differentiation of the Cells

• Glavni autori: Hikaru Yammamoto (Autor), Shigeru Tanaka (Autor), Anna Tanaka (Autor), Izumi Hide (Autor), Takahiro Seki (Autor), Norio Sakai (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2013-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

To examine the functional regulation of serotonin transporter (SERT) by cAMP, we examined whether SERT uptake activity was affected by dibutyryl cAMP (dbcAMP), a cAMP analog, in SERT-transfected RN46A cells derived from embryonic rat raphe neurons. Long-term exposure (> 4 h) of dbcAMP (1 mM) to S...