An Antiherpesviral Host-Directed Strategy Based on CDK7 Covalently Binding Drugs: Target-Selective, Picomolar-Dose, Cross-Virus Reactivity

• Main Authors: DongHoon Yu (Author), Sabrina Wagner (Author), Martin Schütz (Author), Yeejin Jeon (Author), Mooyoung Seo (Author), Jaeseung Kim (Author), Nadine Brückner (Author), Jintawee Kicuntod (Author), Julia Tillmanns (Author), Christina Wangen (Author), Friedrich Hahn (Author), Benedikt B. Kaufer (Author), Frank Neipel (Author), Jan Eickhoff (Author), Bert Klebl (Author), Kiyean Nam (Author), Manfred Marschall (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The repertoire of currently available antiviral drugs spans therapeutic applications against a number of important human pathogens distributed worldwide. These include cases of the pandemic severe acute respiratory coronavirus type 2 (SARS-CoV-2 or COVID-19), human immunodeficiency virus type 1 (HIV...