Optimization of Collagen Chemical Crosslinking to Restore Biocompatibility of Tissue-Engineered Scaffolds

• Autors principals: Mohammad Mirazul Islam (Autor), Dina B. AbuSamra (Autor), Alexandru Chivu (Autor), Pablo Argüeso (Autor), Claes H. Dohlman (Autor), Hirak K. Patra (Autor), James Chodosh (Autor), Miguel González-Andrades (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2021-06-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Collagen scaffolds, one of the most used biomaterials in corneal tissue engineering, are frequently crosslinked to improve mechanical properties, enzyme tolerance, and thermal stability. Crosslinkers such as 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) are compatible with tissu...