Heparin interferes with the uptake of liposomes in glioma

• Main Authors: Thomas S. van Solinge (Author), Kristina Pagh Friis (Author), Killian O'Brien (Author), Romy L. Verschoor (Author), Jeroen van Aarle (Author), Arnold Koekman (Author), Xandra O. Breakefield (Author), Pieter Vader (Author), Raymond Schiffelers (Author), Marike Broekman (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In glioblastoma, a malignant primary brain tumor, liposomes have shown promise in pre-clinical and early phase clinical trials as delivery vehicles for therapeutics. However, external factors influencing cellular uptake of liposomes in glioma cells are poorly understood. Heparin and heparin analogue...