Feasibility exploration of GSH in the treatment of acute hepatic encephalopathy from the aspects of pharmacokinetics, pharmacodynamics, and mechanism

• Main Authors: Kangrui Hu (Author), Yexin Xu (Author), Jiye Fan (Author), Huafang Liu (Author), Chanjuan Di (Author), Feng Xu (Author), Linlin Wu (Author), Ke Ding (Author), Tingting Zhang (Author), Leyi Wang (Author), Haoyu Ai (Author), Lin Xie (Author), Guangji Wang (Author), Yan Liang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Our previous study highlighted the therapeutic potential of glutathione (GSH), an intracellular thiol tripeptide ubiquitous in mammalian tissues, in mitigating hepatic and cerebral damage. Building on this premise, we posited the hypothesis that GSH could be a promising candidate for treating acute...