ABT-263 Reduces Hypertrophic Scars by Targeting Apoptosis of Myofibroblasts

• Main Authors: Xiaolan Yang (Author), Yongqiang Xiao (Author), Chenjian Zhong (Author), Futing Shu (Author), Shichu Xiao (Author), Yongjun Zheng (Author), Zhaofan Xia (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Inhibiting proliferation and inducing apoptosis of myofibroblasts is becoming one of the promising and effective ways to treat hypertrophic scar. ABT-263, as an orally bioavailable BCL-2 family inhibitor, has showed great antitumor characteristics by targeting tumor cell apoptosis. The o...