A Modeling Framework to Characterize Cytokine Release upon T‐Cell-Engaging Bispecific Antibody Treatment: Methodology and Opportunities
T‐cell-engaging bispecific antibodies (T‐BsAbs) are an important class of antibody therapeutics in immuno‐oncology. T‐BsAbs simultaneously bind to CD3 on T cells and a tumor‐associated antigen on tumor cells, activate T cells, and redirect T cells' cytotoxicity against tumor cells. Cytokine rel...
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| Main Authors: | , , , |
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| Format: | Book |
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Wiley,
2019-11-01T00:00:00Z.
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Internet
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |