Cytisine Exerts an Anti-Epileptic Effect via α7nAChRs in a Rat Model of Temporal Lobe Epilepsy

• Main Authors: Jing-jun Zheng (Author), Teng-yue Zhang (Author), Hong-tao Liu (Author), Ze-xin Huang (Author), Jing-mei Teng (Author), Jing-xian Deng (Author), Jia-gui Zhong (Author), Xu Qian (Author), Xin-wen Sheng (Author), Ji-qiang Ding (Author), Shu-qiao He (Author), Xin Zhao (Author), Wei-dong Ji (Author), De-feng Qi (Author), Wei Li (Author), Mei Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Purpose: Temporal lobe epilepsy (TLE) is a common chronic neurological disease that is often invulnerable to anti-epileptic drugs. Increasing data have demonstrated that acetylcholine (ACh) and cholinergic neurotransmission are involved in the pathophysiology of epilepsy. Cytisine, a...