Dihydroartemisinin Alleviates Imiquimod-Induced Psoriasis-like Skin Lesion in Mice Involving Modulation of IL-23/Th17 Axis

• Main Authors: Jiang-Min Liu (Author), Quan-Xin Jin (Author), Manabu Fujimoto (Author), Fang-Fang Li (Author), Lin-Bo Jin (Author), Ran Yu (Author), Guang-Hai Yan (Author), Lian-Hua Zhu (Author), Fan-Ping Meng (Author), Qing-Gao Zhang (Author), Gui-Hua Jin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Psoriasis is a T help 17 (Th17) cell-mediated chronic inflammatory skin disease. Recent studies have shown that dihydroartemisinin (DHA) can significantly reduce experimental autoimmune encephalomyelitis and rheumatoid arthritis by regulating Th17 cells.Objective: To verify whether DHA c...