Modification of the Release of Poorly Soluble Sulindac with the APTES-Modified SBA-15 Mesoporous Silica

• Main Authors: Adrianna Dadej (Author), Aneta Woźniak-Braszak (Author), Paweł Bilski (Author), Hanna Piotrowska-Kempisty (Author), Małgorzata Józkowiak (Author), Małgorzata Geszke-Moritz (Author), Michał Moritz (Author), Daniela Dadej (Author), Anna Jelińska (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The effectiveness of oral drug administration is related to the solubility of a drug in the gastrointestinal tract and its ability to penetrate the biological membranes. As most new drugs are poorly soluble in water, there is a need to develop novel drug carriers that improve the dissolution rate an...