Modification of the Release of Poorly Soluble Sulindac with the APTES-Modified SBA-15 Mesoporous Silica

• Principais autores: Adrianna Dadej (Autor), Aneta Woźniak-Braszak (Autor), Paweł Bilski (Autor), Hanna Piotrowska-Kempisty (Autor), Małgorzata Józkowiak (Autor), Małgorzata Geszke-Moritz (Autor), Michał Moritz (Autor), Daniela Dadej (Autor), Anna Jelińska (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2021-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The effectiveness of oral drug administration is related to the solubility of a drug in the gastrointestinal tract and its ability to penetrate the biological membranes. As most new drugs are poorly soluble in water, there is a need to develop novel drug carriers that improve the dissolution rate an...