miR-7/TGF-β2 axis sustains acidic tumor microenvironment-induced lung cancer metastasis

• Main Authors: Tao Su (Author), Suchao Huang (Author), Yanmin Zhang (Author), Yajuan Guo (Author), Shuwei Zhang (Author), Jiaji Guan (Author), Mingjing Meng (Author), Linxin Liu (Author), Caiyan Wang (Author), Dihua Yu (Author), Hiu-Yee Kwan (Author), Zhiying Huang (Author), Qiuju Huang (Author), Elaine Lai-Han Leung (Author), Ming Hu (Author), Ying Wang (Author), Zhongqiu Liu (Author), Linlin Lu (Author)
• Format: Book
• Published: Elsevier, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acidosis, regardless of hypoxia involvement, is recognized as a chronic and harsh tumor microenvironment (TME) that educates malignant cells to thrive and metastasize. Although overwhelming evidence supports an acidic environment as a driver or ubiquitous hallmark of cancer progression, the unreveal...