Epithelial Cells Attenuate Toll-Like Receptor-Mediated Inflammatory Responses in Monocyte-Derived Macrophage-Like Cells to Mycobacterium tuberculosis by Modulating the PI3K/Akt/mTOR Signaling Pathway

• Asıl Yazarlar: Yi Yang (Yazar), Yingfei Sun (Yazar), Jinrui Xu (Yazar), Kangda Bao (Yazar), Meihui Luo (Yazar), Xiaoming Liu (Yazar), Yujiong Wang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2018-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Both alveolar macrophages (AMs) and alveolar epithelial cells (AECs) are main targets of Mycobacterium tuberculosis (M. tuberculosis (Mtb)). Intercellular communications between mucosal AECs and AMs have important implications in cellular responses to exogenous insults. However, molecular mechanisms...