Nrf2 Activates Augmenter of Liver Regeneration (ALR) via Antioxidant Response Element and Links Oxidative Stress to Liver Regeneration

• Main Authors: Rania Dayoub (Author), Arndt Vogel (Author), Jutta Schuett (Author), Madeleine Lupke (Author), Susannah M. Spieker (Author), Nadja Kettern (Author), Eberhard Hildt (Author), Michael Melter (Author), Thomas S. Weiss (Author)
• Format: Book
• Published: BMC, 2013-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Liver regeneration can be impaired by permanent oxidative stress and activation of nuclear factor erythroid 2-related factor 2 (Nrf2), known to regulate the cellular antioxidant response, and has been shown to improve the process of liver regeneration. A variety of factors regulate hepatic...