The Effects of Anti-retroviral Therapy on Epigenetic Age Acceleration Observed in HIV-1-infected Adults

• Main Authors: Mary E. Sehl (Author), Tammy M. Rickabaugh (Author), Roger Shih (Author), Otoniel Martinez-Maza (Author), Steve Horvath (Author), Christina M. Ramirez (Author), Beth D. Jamieson (Author)
• Format: Book
• Published: Case Western Reserve University, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: HIV-1 infection is associated with acceleration of age-related methylation patterns in peripheral blood and brain of infected individuals although the relative contributions of HIV-1 infection versus its treatment to the observed accelerations in biological aging have not yet been invest...