Fisetin Attenuates Diabetic Nephropathy-Induced Podocyte Injury by Inhibiting NLRP3 Inflammasome

• Main Authors: Wenmin Dong (Author), Chenglin Jia (Author), Ji Li (Author), Yi Zhou (Author), Yun Luo (Author), Jibo Liu (Author), Zhiguo Zhao (Author), Jiaqi Zhang (Author), Shan Lin (Author), Ying Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetic nephropathy (DN) is one of the primary complications of diabetes. Fisetin is a flavonoid polyphenol that is present in several vegetables and fruits. The present study investigated the mechanisms of fisetin in DN-induced podocyte injury both in vitro and in vivo. The results revealed that f...