Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis

• Main Authors: Yuanyuan Liu (Author), Wenshan Zhong (Author), Jinming Zhang (Author), Weimou Chen (Author), Ye lu (Author), Yujie Qiao (Author), Zhaojin Zeng (Author), Haohua Huang (Author), Shaoxi Cai (Author), Hangming Dong (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Idiopathic pulmonary fibrosis is a progressive fatal disease characterized by interstitial remodeling, with high lethality and a lack of effective medical therapies. Tetrandrine has been proposed to present anti-fibrotic effects, but the efficacy and mechanisms have not been systematically evaluated...