Live attenuated Salmonella Typhimurium with monophosphoryl lipid A retains ability to induce T-cell and humoral immune responses against heterologous polysaccharide of Shigella flexneri 2a

Shigella flexneri 2a (Sf2a) is one of the most frequently isolated Shigella strains that causes the endemic shigellosis in developing countries. In this study, we used recombinant attenuated Salmonella vaccine (RASV) strains to deliver Sf2a O-antigen and characterized the immune responses induced by...

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Main Authors: Qing Liu (Author), Huali Su (Author), Xiaoping Bian (Author), Shifeng Wang (Author), Qingke Kong (Author)
Format: Book
Published: Elsevier, 2020-07-01T00:00:00Z.
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