Influence of light-dark cycle on delayed recovery from isoflurane anesthesia induced by hypnotics in mice

• Main Authors: Atsunobu Sugano (Author), Hiroki Murai (Author), Syunpei Horiguchi (Author), Yuma Yoshimoto (Author), Yuki Amano (Author), Tomoki Kimura (Author), Yoshinori Iba (Author)
• Format: Book
• Published: Elsevier, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We previously reported that brotizolam, but not suvorexant, delayed recovery from isoflurane anesthesia in mice. However, the effects of hypnotics may be altered by the circadian rhythm. Locomotor activity was measured using sighted (ICR and C57BL/6J) and blind (FVB/N and C3H/HeN) mice, and the effe...