Copy number variation of IL17RA gene and its association with the ankylosing spondylitis risk in Iranian patients: a case-control study

• Main Authors: Hamideh Aghaei (Author), Elham Farhadi (Author), Maryam Akhtari (Author), Sara Shahba (Author), Shayan Mostafaei (Author), Ahmadreza Jamshidi (Author), Shiva Poursani (Author), Mahdi Mahmoudi (Author), Mohammad Hossein Nicknam (Author)
• Format: Book
• Published: BMC, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ankylosing spondylitis (AS) is considered as a subtype of spondyloarthritis (SpA) that mainly leads to fatigue, stiffness, spinal ankylosis, and impaired physical functions with reduced quality of life. Interleukin (IL)-17A provokes additional inflammatory mediators and recruits...