COX-2 is required to mediate crosstalk of ROS-dependent activation of MAPK/NF-κB signaling with pro-inflammatory response and defense-related NO enhancement during challenge of macrophage-like cell line with Giardia duodenalis.

• Κύριοι συγγραφείς: Yudan Zhao (Συγγραφέας), Yongwu Yang (Συγγραφέας), Min Liu (Συγγραφέας), Xuening Qin (Συγγραφέας), Xiran Yu (Συγγραφέας), Huimin Zhao (Συγγραφέας), Xiaoyun Li (Συγγραφέας), Wei Li (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Public Library of Science (PLoS), 2022-04-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Giardia duodenalis, the causative agent of giardiasis, is among the most important causes of waterborne diarrheal diseases around the world. Giardia infection may persist over extended periods with intestinal inflammation, although minimal. Cyclooxygenase (COX)-2 is well known as an important induce...