Synthesis, Screening and Characterization of Novel Potent Arp2/3 Inhibitory Compounds Analogous to CK-666

Synthesis, Screening and Characterization of Novel Potent Arp2/3 Inhibitory Compounds Analogous to CK-666

Branched actin networks polymerized by the Actin-related protein 2 and 3 (Arp2/3) complex play key roles in force generation and membrane remodeling. These networks are particularly important for cell migration, where they drive membrane protrusions of lamellipodia. Several Arp2/3 inhibitory compoun...

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Main Authors: Artem I. Fokin (Author), Roman N. Chuprov-Netochin (Author), Alexander S. Malyshev (Author), Stéphane Romero (Author), Marina N. Semenova (Author), Leonid D. Konyushkin (Author), Sergey V. Leonov (Author), Victor V. Semenov (Author), Alexis M. Gautreau (Author)
Format: Book
Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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