Synthesis and Antiproliferative Effect of 3,4,5-Trimethoxylated Chalcones on Colorectal and Prostatic Cancer Cells

• Main Authors: Cécile Letulle (Author), François-Xavier Toublet (Author), Aline Pinon (Author), Soufyane Hba (Author), Aurélie Laurent (Author), Vincent Sol (Author), Catherine Fagnère (Author), Benjamin Rioux (Author), Florent Allais (Author), Sophie Michallet (Author), Laurence Lafanechère (Author), Youness Limami (Author), Mounia Oudghiri (Author), Mohamed Othman (Author), Adam Daïch (Author), Bertrand Liagre (Author), Ata Martin Lawson (Author), Christelle Pouget (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the context of designing innovative anticancer agents, the synthesis of a series of chalcones bearing a 3,4,5-trimethoxylated A ring and a variety of B rings, including phenols and original heterocycles such as chromones, was conducted. For this end, Claisen-Schmidt condensation was performed in...