Long-chain acyl-CoA synthetase-4 regulates endometrial decidualization through a fatty acid β-oxidation pathway rather than lipid droplet accumulation

• Main Authors: Hongshuo Zhang (Author), Qianyi Sun (Author), Haojie Dong (Author), Zeen Jin (Author), Mengyue Li (Author), Shanyuan Jin (Author), Xiaolan Zeng (Author), Jianhui Fan (Author), Ying Kong (Author)
• Format: Book
• Published: Elsevier, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Lipid metabolism plays an important role in early pregnancy, but its effects on decidualization are poorly understood. Fatty acids (FAs) must be esterified by fatty acyl-CoA synthetases to form biologically active acyl-CoA in order to enter the anabolic and/or catabolic pathway. Long-chai...