Down syndrome: searching for the genetic culprits

• Glavni autori: Eva Lana-Elola (Autor), Sheona D. Watson-Scales (Autor), Elizabeth M. C. Fisher (Autor), Victor L. J. Tybulewicz (Autor)
• Format: Knjiga
• Izdano: The Company of Biologists, 2011-09-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Down syndrome (DS) is caused by trisomy of human chromosome 21 (Hsa21) and results in a large number of phenotypes, including learning difficulties, cardiac defects, distinguishing facial features and leukaemia. These are likely to result from an increased dosage of one or more of the ∼310 genes pre...