AAV-glycine receptor α3 alleviates CFA-induced inflammatory pain by downregulating ERK phosphorylation and proinflammatory cytokine expression in SD rats

• Main Authors: Hung-Chen Wang (Author), Kuang-I Cheng (Author), Kuang-Yi Tseng (Author), Aij-Lie Kwan (Author), Lin-Li Chang (Author)
• Formato: Libro
• Publicado: BMC, 2023-02-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Abstract Background Glycine receptors (GlyRs) play key roles in the processing of inflammatory pain. The use of adeno-associated virus (AAV) vectors for gene therapy in human clinical trials has shown promise, as AAV generally causes a very mild immune response and long-term gene transfer, and there...