Blockage of Eosinopoiesis by IL-17A Is Prevented by Cytokine and Lipid Mediators of Allergic Inflammation

• Главные авторы: Pedro Xavier-Elsas (Автор), Bianca de Luca (Автор), Túlio Queto (Автор), Bruno Marques Vieira (Автор), Daniela Masid- (Автор), Elizabeth Chen Dahab (Автор), José Carlos Alves Filho (Автор), Fernando Q. Cunha (Автор), Maria Ignez C. Gaspar-Elsas (Автор)
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• Опубликовано: Hindawi Limited, 2015-01-01T00:00:00Z.
• Предметы: article
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Interleukin- (IL-) 17A, a pleiotropic mediator of inflammation and autoimmunity, potently stimulates bone-marrow neutrophil production. To explore IL-17A effects on eosinopoiesis, we cultured bone-marrow from wild-type mice, or mutants lacking inducible nitric oxide synthase (iNOS−/−), CD95 (lpr), I...