Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine

• Main Authors: Nikhil T. Awatade (Author), Sharon L. Wong (Author), Chris K. Hewson (Author), Laura K. Fawcett (Author), Anthony Kicic (Author), Adam Jaffe (Author), Shafagh A. Waters (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cystic fibrosis (CF) is an inherited disorder where individual disease etiology and response to therapeutic intervention is impacted by CF transmembrane regulator (CFTR) mutations and other genetic modifiers. CFTR regulates multiple mechanisms in a diverse range of epithelial tissues. In this Review...