Glutamyl-Prolyl-tRNA Synthetase Regulates Epithelial Expression of Mesenchymal Markers and Extracellular Matrix Proteins: Implications for Idiopathic Pulmonary Fibrosis

• Main Authors: Dae-Geun Song (Author), Doyeun Kim (Author), Jae Woo Jung (Author), Seo Hee Nam (Author), Ji Eon Kim (Author), Hye-Jin Kim (Author), Jong Hyun Kim (Author), Cheol-Ho Pan (Author), Sunghoon Kim (Author), Jung Weon Lee (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Idiopathic pulmonary fibrosis (IPF), a chronic disease of unknown cause, is characterized by abnormal accumulation of extracellular matrix (ECM) in fibrotic foci in the lung. Previous studies have shown that the transforming growth factor β1 (TGFβ1) and signal transducers and activators of transcrip...