CPS1 augments hepatic glucagon response through CaMKII/FOXO1 pathway

• Main Authors: Xiao-Meng Sun (Author), Xin Wu (Author), Meng-Guang Wei (Author), Li-Zeng Zhu (Author), Wen-hui Wu (Author), Xin-Yue Zhou (Author), Lian-Wen Qi (Author), Qun Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Elevated glucagon levels are a characteristic feature of type 2 diabetes. This abnormal increase in glucagon can lead to an accelerated rate of gluconeogenesis. Glucagon also stimulates hepatic metabolism of amino acids, particularly promoting the formation of urea. The specific role o...