SPC Liposomes as Possible Delivery Systems for Improving Bioavailability of the Natural Sesquiterpene β-Caryophyllene: Lamellarity and Drug-Loading as Key Features for a Rational Drug Delivery Design

• Главные авторы: Antonella Di Sotto (Автор), Patrizia Paolicelli (Автор), Martina Nardoni (Автор), Lorena Abete (Автор), Stefania Garzoli (Автор), Silvia Di Giacomo (Автор), Gabriela Mazzanti (Автор), Maria Antonietta Casadei (Автор), Stefania Petralito (Автор)
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• Опубликовано: MDPI AG, 2018-12-01T00:00:00Z.
• Предметы: article
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The natural sesquiterpene β-caryophyllene (CRY) has been highlighted to possess interesting pharmacological potentials, particularly due to its chemopreventive and analgesic properties. However, the poor solubility of this sesquiterpene in aqueous fluids can hinder its uptake into cells, resulting i...