Transdermal agomelatine microemulsion gel: pyramidal screening, statistical optimization and in vivo bioavailability

Agomelatine is a new antidepressant having very low oral drug bioavailability less than 5% due to being liable to extensive hepatic 1st pass effect. This study aimed to deliver agomelatine by transdermal route through formulation and optimization of microemulsion gel. Pyramidal screening was perform...

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Bibliographic Details
Main Authors: Mayada Said (Author), Ibrahim Elsayed (Author), Ahmed A. Aboelwafa (Author), Ahmed H. Elshafeey (Author)
Format: Book
Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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