Hamster neogenin, a host-cell protein contained in a respiratory syncytial virus candidate vaccine, induces antibody responses in rabbits but not in clinical trial participants

• Main Authors: Ann-Muriel Steff (Author), Chanel Cadieux-Dion (Author), Gaël de Lannoy (Author), Maria Key Prato (Author), Xavier Czeszak (Author), Bruno André (Author), Dominique C Ingels (Author), Marc Louckx (Author), Walthère Dewé (Author), Marta Picciolato (Author), Koen Maleux (Author), Laurence Fissette (Author), Ilse Dieussaert (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A recombinant respiratory syncytial virus (RSV) fusion glycoprotein candidate vaccine (RSV-PreF) manufactured in Chinese hamster ovary cells was developed for immunization of pregnant women, to protect newborns against RSV disease through trans-placental antibody transfer. Traces of a host-cell prot...