γ-Glutamylcysteine Exerts Neuroprotection Effects against Cerebral Ischemia/Reperfusion Injury through Inhibiting Lipid Peroxidation and Ferroptosis

• Главные авторы: Ruyi Zhang (Автор), Jianzhen Lei (Автор), Luyao Chen (Автор), Yanan Wang (Автор), Guocui Yang (Автор), Zhimin Yin (Автор), Lan Luo (Автор)
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• Опубликовано: MDPI AG, 2022-08-01T00:00:00Z.
• Предметы: article
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Ferroptosis is a non-apoptotic form of cell death driven by iron-dependent lipid peroxidation. Recent evidence indicates that inhibiting ferroptosis could alleviate cerebral ischemia/reperfusion (CIR) injury. γ-glutamylcysteine (γ-GC), an intermediate of glutathione (GSH) synthesis, can upregulate G...