Effectiveness of BNT162b2 COVID-19 vaccination in prevention of hospitalisations and severe disease in adults with SARS-CoV-2 Delta (B.1.617.2) and Omicron (B.1.1.529) variant between June 2021 and July 2022: A prospective test negative case-control studyResearch in context

• Main Authors: Anastasia Chatzilena (Author), Catherine Hyams (Author), Rob Challen (Author), Robin Marlow (Author), Jade King (Author), David Adegbite (Author), Jane Kinney (Author), Madeleine Clout (Author), Nick Maskell (Author), Jennifer Oliver (Author), Leon Danon (Author), Adam Finn (Author), Anna Morley (Author), Amelia Langdon (Author), Anabella Turner (Author), Anya Mattocks (Author), Bethany Osborne (Author), Charli Grimes (Author), Claire Mitchell (Author), Emma Bridgeman (Author), Emma Scott (Author), Fiona Perkins (Author), Francesca Bayley (Author), Gabriella Ruffino (Author), Gabriella Valentine (Author), Grace Tilzey (Author), Johanna Kellett Wright (Author), Julia Brzezinska (Author), Julie Cloake (Author), Katarina Milutinovic (Author), Kate Helliker (Author), Katie Maughan (Author), Kazminder Fox (Author), Konstantina Minou (Author), Lana Ward (Author), Leah Fleming (Author), Leigh Morrison (Author), Lily Smart (Author), Louise Wright (Author), Lucy Grimwood (Author), Maddalena Bellavia (Author), Marianne Vasquez (Author), Maria Garcia Gonzalez (Author), Milo Jeenes-Flanagan (Author), Natalie Chang (Author), Niall Grace (Author), Nicola Manning (Author), Oliver Griffiths (Author), Pip Croxford (Author), Peter Sequenza (Author), Rajeka Lazarus (Author), Rhian Walters (Author), Robyn Heath (Author), Rupert Antico (Author), Sandi Nammuni Arachchge (Author), Seevakumar Suppiah (Author), Taslima Mona (Author), Tawassal Riaz (Author), Vicki Mackay (Author), Zandile Maseko (Author), Zoe Taylor (Author), Zsolt Friedrich (Author), Zsuzsa Szasz-Benczur (Author)
• Format: Book
• Published: Elsevier, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Background: Whilst other studies have reported the effectiveness of mRNA vaccination against hospitalisation, including emergency department or intensive care admission, few have assessed effectiveness against other more clinically robust indices of COVID-19 severity. Methods: A prospective...