Disease severity in patients infected with Leishmania mexicana relates to IL-1β.

• Main Authors: Edith A Fernández-Figueroa (Author), Claudia Rangel-Escareño (Author), Valeria Espinosa-Mateos (Author), Karol Carrillo-Sánchez (Author), Norma Salaiza-Suazo (Author), Georgina Carrada-Figueroa (Author), Santiago March-Mifsut (Author), Ingeborg Becker (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leishmania mexicana can cause both localized (LCL) and diffuse (DCL) cutaneous leishmaniasis, yet little is known about factors regulating disease severity in these patients. We analyzed if the disease was associated with single nucleotide polymorphisms (SNPs) in IL-1β (-511), CXCL8 (-251) and/or th...