Proliferative epithelial changes in tumour adjacent tissue in Sri Lankan women with breast carcinoma: do morphological changes support molecular models of breast carcinogenesis?

• Autori principali: Indumini Maheshika Jinadasa (Autore), Harshima Disvini Wijesinghe (Autore), Modini Manohari Abeydera Jayawickrama (Autore), Menaka Dilani Samarawickrama Lokuhetty (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2022-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background The multistep molecular model of breast carcinogenesis is based on the oestrogen receptor(ER) status of the tumour. Its two main arms comprise ER-positive and ER-negative breast carcinomas(BCa), which are associated with Nottingham grade(NG) of the tumour and different proliferat...