Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2Rγnull mice engrafted with human peripheral blood mononuclear cells

• Main Authors: Thomas Nolte (Author), Maryam Zadeh-Khorasani (Author), Orkhan Safarov (Author), Franziska Rueff (Author), Rita Varga (Author), Nadja Herbach (Author), Rüdiger Wanke (Author), Andreas Wollenberg (Author), Thomas Mueller (Author), Roswitha Gropp (Author), Eckhard Wolf (Author), Matthias Siebeck (Author)
• Format: Book
• Published: The Company of Biologists, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Animal models mimicking human diseases have been used extensively to study the pathogenesis of autoimmune diseases and the efficacy of potential therapeutics. They are, however, limited with regard to their similarity to the human disease and cannot be used if the antagonist and its cognate...