Elimination of macrophages reduces glutaraldehyde‐fixed porcine heart valve degeneration in mice subdermal model

• Main Authors: Zongtao Liu (Author), Yixuan Wang (Author), Fei Xie (Author), Xing Liu (Author), Fei Li (Author), Nianguo Dong (Author)
• פורמט: ספר
• יצא לאור: Wiley, 2021-02-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Glutaraldehyde‐fixed porcine heart valve (GPHV) calcify and deteriorate over time. The aim of this study was to explore the roles macrophages play in mediating calcification and degeneration of the valve's connective tissue matrix. GPHV were implanted subcutaneously in the abdomens of...