Elimination of macrophages reduces glutaraldehyde‐fixed porcine heart valve degeneration in mice subdermal model

• मुख्य लेखकों: Zongtao Liu (लेखक), Yixuan Wang (लेखक), Fei Xie (लेखक), Xing Liu (लेखक), Fei Li (लेखक), Nianguo Dong (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2021-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Glutaraldehyde‐fixed porcine heart valve (GPHV) calcify and deteriorate over time. The aim of this study was to explore the roles macrophages play in mediating calcification and degeneration of the valve's connective tissue matrix. GPHV were implanted subcutaneously in the abdomens of...