Sequence-based engineering of pH-sensitive antibodies for tumor targeting or endosomal recycling applications
The engineering of pH-sensitive therapeutic antibodies, particularly for improving effectiveness and specificity in acidic solid-tumor microenvironments, has recently gained traction. While there is a justified need for pH-dependent immunotherapies, current engineering techniques are tedious and lab...
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Taylor & Francis Group,
2024-12-01T00:00:00Z.
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