Tetrathiomolybdate Treatment Attenuates Bleomycin-Induced Angiogenesis and Lung Pathology in a Sheep Model of Pulmonary Fibrosis

• Main Authors: Habtamu B. Derseh (Author), Kopiyawaththage U. E. Perera (Author), Sasika N. Vithana Dewage (Author), Andrew Stent (Author), Emmanuel Koumoundouros (Author), Louise Organ (Author), Charles N. Pagel (Author), Ken J. Snibson (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Idiopathic pulmonary fibrosis (IPF) is a progressive chronic lung disease characterized by excessive extracellular matrix (ECM) deposition in the parenchyma of the lung. Accompanying the fibrotic remodeling, dysregulated angiogenesis has been observed and implicated in the development and progressio...