Rhein Relieves Oxidative Stress in an Aβ1-42 Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis

Neuronal mitochondrial oxidative stress induced by β-amyloid (Aβ) is an early event of Alzheimer's disease (AD). Emerging evidence has shown that antioxidant therapy represents a promising therapeutic strategy for the treatment of AD. In this study, we investigated the antioxidant activity of r...

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Main Authors: Zhihui Yin (Author), Xinyue Geng (Author), Zhengyi Zhang (Author), Ying Wang (Author), Xiaoyan Gao (Author)
Format: Book
Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
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3rd Floor Main Library

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