Azithromycin and Sildenafil May Have Protective Effects on Retinal Ganglion Cells via Different Pathways: Study in a Rodent Microbead Model

• Main Authors: Tal Corina Sela (Author), Alon Zahavi (Author), Moran Friedman-Gohas (Author), Shirel Weiss (Author), Amir Sternfeld (Author), Astrid Ilguisonis (Author), Danielle Badash (Author), Noa Geffen (Author), Ron Ofri (Author), Yaniv BarKana (Author), Nitza Goldenberg-Cohen (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Decreased blood flow to the optic nerve (ON) and neuroinflammation are suggested to play an important role in the pathophysiology of glaucoma. This study investigated the potential neuroprotective effect of azithromycin, an anti-inflammatory macrolide, and sildenafil, a selective phosphodiesterase-5...