Evaluation of Anticonvulsant Activity of Dual COX-2/5-LOX Inhibitor Darbufelon and Its Novel Analogues

• Main Authors: Mariia Mishchenko (Author), Sergiy Shtrygol' (Author), Andrii Lozynskyi (Author), Semen Khomyak (Author), Volodymyr Novikov (Author), Olexandr Karpenko (Author), Serhii Holota (Author), Roman Lesyk (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuroinflammation is an integral part of epilepsy pathogenesis and other convulsive conditions, and non-steroidal anti-inflammatory drugs (NSAIDs) present a potent tool for the contemporary search and design of novel anticonvulsants. In the present paper, evaluation of the anticonvulsant activity of...