UHPLC-QQQ-MS/MS assay for the quantification of dianthrones as potential toxic markers of Polygonum multiflorum Thunb: applications for the standardization of traditional Chinese medicines (TCMs) with endogenous toxicity

• Main Authors: Jian-Bo Yang (Author), Yun-Fei Song (Author), Yue Liu (Author), Hui-Yu Gao (Author), Qi Wang (Author), Ying Wang (Author), Xian-Long Cheng (Author), Tian-Tian Zuo (Author), Xiao-Wen Hu (Author), Feng Wei (Author), Hong-Tao Jin (Author), Shu-Ting Wang (Author), Shuang-Cheng Ma (Author)
• Format: Book
• Published: BMC, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The raw and processed roots of Polygonum multiflorum Thunb (PM) are commonly used in clinical practice to treat diverse diseases; however, reports of hepatotoxicity induced by Polygoni Multiflori Radix (PMR) and Polygoni Multiflori Radix Praeparata (PMRP) have emerged worldwide....